The aim of the study was to evaluate the potential antibacterial activity of Desmodium gangeticum whole plant ethanolic extract (DGEE) using in vitro antibacterial models. The in vitro antibacterial activity was performed by agar disc diffusion method .In antibacterial method DGEE was used at different concentrations 2,4,6,8,mg/ml and standard streptomycin (30µg/ml )was evaluated on bacterial strains like Bacillus subtilus ATCC 6633, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC27853, Salmonella typhimurium ATCC 23564.The anti bacterial activity of DGEE showed concentration dependent activity against all the tested bacterium with the zone of inhibition at various concentrations. Thus the finding revealed the medicinal potential of DGEE against various infectious diseases to develop a drug. The ethanolic extract (8mg/ml) showed broad-spectrum antibacterial activity against gram positive and gram negative bacteria. The results were compared with the standard drug streptomycin (30µg/ml).
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